Mutation detection in saliva from oral cancer patients | Ahmed AA, et al | Oral Oncology | Apr. 2024

Ahmed AA, Sborchia M, Bye H, Roman-Escorza M, Amar A, Henley-Smith R, et al. Mutation detection in saliva from oral cancer patients. Oral Oncology. 2024;151:106717.

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Abstract

The incidence of head and neck squamous cell carcinoma (HNSCC) continues to increase and although advances have been made in treatment, it still has a poor overall survival with local relapse being common. Conventional imaging methods are not efficient at detecting recurrence at an early stage when still potentially curable. The aim of this study was to test the feasibility of using saliva to detect the presence of oral squamous cell carcinoma (OSCC) and to provide additional evidence for the potential of this approach.