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The art of maximizing cell-free DNA yield from plasma
July 14, 2021. Reviewed by Celina Whalley, April 26, 2024 Cell-free DNA testing: What you need to consider before you start A successful next generation sequencing assay using cell free DNA (cfDNA) relies heavily on the pre-analytical steps; sample collection, storage and cfDNA extraction. The pre-analytical products developed at Nonacus have been designed to maximize…
Read MoreJune 14, 2021. Reviewed by Celina Whalley, April 26, 2024. Reducing the need for prophylactic anti-D treatment for pregnant women Non-invasive prenatal testing (NIPT) using cell-free fetal DNA (cfDNA) in maternal plasma is being used to determine fetal RhD blood group antigen status so that RhD-negative pregnant women can avoid receiving antenatal anti-D if they…
Read MoreMay 27, 2020. Reviewed by Victoria Simms, April 22, 2024 Coeliac disease is a serious, autoimmune disease of the gut caused by a reaction to eating gluten. It causes damage to the lining of the gut and means that the body can’t properly absorb nutrients from food. It affects 1 in 100 people in Europe…
Read MoreWhy cfDNA has caused a revolution in genetic diagnostics
Written November 11, 2021. Revised by Celina Whalley, April 26, 2024 There’s been a revolution. It comes in the form of cell free DNA (cfDNA), which is changing patient pathways for the better across the globe. Due to its nature, cfDNA is considered as an excellent biomarker and source of genetic information. Cell free DNA…
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