Custom panels

726P Circulating cell-free DNA-based biomarkers as a new tool for prognosis and surveillance of adrenocortical carcinoma | Ronchi CL, et al. | Annals of Oncology | Oct. 2023

By Celina Whalley / April 3, 2024 / Comments Off on 726P Circulating cell-free DNA-based biomarkers as a new tool for prognosis and surveillance of adrenocortical carcinoma | Ronchi CL, et al. | Annals of Oncology | Oct. 2023

Ronchi CL, Lippert J, Smith G, Altieri B, Elhassan YS, Landwehr LS, et al. 726P Circulating cell-free DNA-based biomarkers as a new tool for prognosis and surveillance of adrenocortical carcinoma. Annals of Oncology. 2023;34:S500. Nonacus product: Custom panels Background Adrenocortical carcinoma (ACC) is a rare aggressive endocrine cancer with heterogeneous behaviour. Disease surveillance relies on…

Read More

OR04-5 Circulating cell-free DNA-based biomarkers For prognostication and disease surveillance in adrenocortical carcinoma | Altieri B, et al | Journal of the Endocrine Society | Nov. 2022

By Celina Whalley / March 28, 2024 / Comments Off on OR04-5 Circulating cell-free DNA-based biomarkers For prognostication and disease surveillance in adrenocortical carcinoma | Altieri B, et al | Journal of the Endocrine Society | Nov. 2022

Lippert J, Smith G, Appenzeller S, Landwehr LS, Prete A, Steinhauer S, et al. Circulating cell-free DNA-based biomarkers for prognostication and disease monitoring in adrenocortical carcinoma. European Journal of Endocrinology. 2024;lvae022. Nonacus products: Sample collection and isolation / Custom panels Abstract Adrenocortical carcinoma (ACC) is a rare aggressive cancer with heterogeneous behaviour. Disease surveillance relies on…

Read More

Custom panel implementation in patients with non-syndromic autism spectrum disorders in the clinical routine of a tertiary hospital | Sandoval-Talamantes AK, et al | Genes | Nov. 2023

By Celina Whalley / March 27, 2024 / Comments Off on Custom panel implementation in patients with non-syndromic autism spectrum disorders in the clinical routine of a tertiary hospital | Sandoval-Talamantes AK, et al | Genes | Nov. 2023

Sandoval-Talamantes AK, Tenorio-Castaño JA, Santos-Simarro F, Adán C, Fernández-Elvira M, García-Fernández L, et al. NGS Custom Panel Implementation in Patients with Non-Syndromic Autism Spectrum Disorders in the Clinical Routine of a Tertiary Hospital. Genes. 2023 ;14(11):2091. Nonacus product: Custom panels Abstract Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by deficiencies in…

Read More

Coincidence of primary adrenocortical carcinoma and melanoma: three CASE reports | Ko YL, et al | BMC Endocrine Disorders | Jan. 2023

By nonacus-developer / August 25, 2023 / Comments Off on Coincidence of primary adrenocortical carcinoma and melanoma: three CASE reports | Ko YL, et al | BMC Endocrine Disorders | Jan. 2023

Ko YL, Kumar V, Lippert J, Diaz-Cano S, Skordilis K, Kimpel O, Coincidence of primary adrenocortical carcinoma and melanoma: three CASE reports. BMC Endocrine Disorders. 2023 Jan;23(1):4.   Nonacus products:  Custom panels Background Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a heterogeneous prognosis, while adrenal metastasis from other primary cancers, including melanoma, may…

Read More

Next generation sequencing reveals novel genetic variants (SRY, DMRT1, NR5A1, DHH, DHX37) in adults with 46,XY DSD | Buonocore F, et al | Journal of the Endocrine Society | Dec. 2019

By nonacus-developer / August 25, 2023 / Comments Off on Next generation sequencing reveals novel genetic variants (SRY, DMRT1, NR5A1, DHH, DHX37) in adults with 46,XY DSD | Buonocore F, et al | Journal of the Endocrine Society | Dec. 2019

Buonocore F, Clifford-Mobley O, King TF, Striglioni N, Man E, Suntharalingham JP, et al. Next-generation sequencing reveals novel genetic variants (SRY, DMRT1, NR5A1, DHH, DHX37) in adults with 46, XY DSD. Journal of the Endocrine Society. 2019;12:2341-60. Nonacus Products: Custom panels Context The genetic basis of human sex development is slowly being elucidated, and >40…

Read More

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR | Ghorashian S, et al | Nature medicine | Sep. 2019

By nonacus-developer / August 25, 2023 / Comments Off on Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR | Ghorashian S, et al | Nature medicine | Sep. 2019

Nonacus Products: Cell3 Target: Oncology Abstract Chimeric antigen receptor (CAR)-modified T cells targeting CD19 demonstrate unparalleled responses in relapsed/refractory acute lymphoblastic leukemia (ALL), but toxicity, including cytokine-release syndrome (CRS) and neurotoxicity, limits broader application. Moreover, 40-60% of patients relapse owing to poor CAR T cell persistence or emergence of CD19− clones. Some factors, including the choice…

Read More